The fifth annual HIV/HCV Co-infection Awareness Day (HHCAD) is being commemorated on Tuesday, May 17. The AIDS Education and Training Centers (AETC) Co-infection Community of Practice and Learning first designated HHCAD in 2018 to raise awareness about this common co-infection among people with HIV. The U.S. Centers for Disease Control and Prevention (CDC) has estimated that about one-quarter of all persons with HIV in the U.S. are co-infected with the hepatitis C virus (HCV). According to AETC, “HIV/HCV Co-infection Awareness Day provides an opportunity for healthcare providers and health departments to educate colleagues, constituents, and clients about the importance of curing HCV infection in people living with HIV.”
Healthcare professionals can consult HIV/HCV Co-infection: An AETC National Curriculum to increase their knowledge about HIV/HCV co-infection prevention, screening, diagnosis and treatment, as well as the barriers and co-factors that impede optimal treatment outcomes for co-infected people of color, in particular.
To further increase knowledge and awareness of HIV/HCV co-infection and to support activities commemorating HHCAD, we have compiled the following annotated list of online resources. For additional information on this topic, you can also visit NEAETC’s Online HIV Resource Library page focusing on HIV and Hepatitis C Co-infection.
Fact Sheets, Infographics, and Briefs
HIV and Hepatitis C (HIVinfo) – This fact sheet describes what HCV is, how it is transmitted, the connection between HIV and HCV, and HCV prevention, testing, symptoms, and treatment. Also available in Spanish.
HIV and Hepatitis B and Hepatitis C Coinfection (HIV.gov) – This web page in question-and-answer format includes information on hepatitis B and C transmission, prevention, and treatment, as well as recommended hepatitis testing for people with HIV.
People Coinfected with HIV and Viral Hepatitis (CDC) – This web page provides an overview of HIV co-infection with either hepatitis A, hepatitis B, or HCV. It also includes a discussion of hepatitis vaccination and testing, as well as links to guidelines and recommendations for the management of HIV and viral hepatitis co-infection.
HIV and Hepatitis C Coinfection (Department of Veterans Affairs) – This fact sheet in question-and-answer format provides basic information about HIV, HCV, and co-infection, together with information about the risk factors, prevention, transmission, and treatment of HIV-HCV co-infection. Tips for living a healthy life with co-infection are also provided.
Barriers to Curing HCV Among Coinfected People with HIV (AETC National Coordinating Resource Center) – According to AETC, this infographic “addresses some of the barriers to curing HCV infection among co-infected people with HIV. It highlights provider, patient, and financial/systems barriers, provides information for HCV treatment initiation based on the latest treatment guidelines, and offers additional considerations to help health professionals navigate through some of the challenges outlined.”
Guidelines and Recommendations
Considerations for Antiretroviral Use in Patients with Coinfections: Hepatitis C Virus/HIV Coinfection (HHS) – This section of the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV includes recommendations for screening people living with HIV for viral hepatitis, including HCV; vaccinating for HAV and HBV; providing antiretroviral therapy for HIV to co-infected persons; and concurrent treatment of HIV and HCV.
Patients with HIV/HCV Coinfection (American Association for the Study of Liver Diseases and Infectious Diseases Society of America) – This is a section of HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C. It includes tables of recommendations on managing interactions of the drugs used to treat HCV and HIV, as well as guidance regarding regimens not recommended for persons with HIV/HCV co-infection.
Curricula, Toolkits, and Other Materials
HIV/HCV Co-infection: An AETC National Curriculum – This curriculum for healthcare providers and trainers of healthcare providers is designed “to increase their knowledge on HIV and HCV co-infection among people of color in the U.S. and its territories,” according to AETC. The curriculum has the following six core modules: epidemiology; prevention; screening, testing, and diagnosis; HCV treatment; recommendations for subpopulations of HIV/HCV co-infected persons; and addressing barriers for co-infected people of color.
Treatment of HCV in Persons with HIV Coinfection (University of Washington) – This self-study module of the Hepatitis C Online website provides background on HCV/HIV co-infection, a review of data on HCV treatment in people with HIV, recommended HCV treatment in persons with HIV co-infection, treatment of HIV in persons with HCV co-infection, drug interactions with HIV/HCV co-infection treatment, a summary of key points, and an extensive reference list.
Hepatitis C Prescriber Toolkit (TargetHIV, HRSA) – This toolkit has state-specific resources to help providers navigate the health coverage requirements that affect the prescription of HCV treatment. It includes information about prescribing restrictions; Ryan White HIV/AIDS Program AIDS Drug Assistance Program coverage; and Medicare coverage.
Myth-Busting HCV Treatment: Demystifying HCV Treatment in At-Risk Populations (New England AETC, January 2022) – This part of the “Myth-Busting HCV Treatment” series explores how advances in HCV treatment have affected the clinical management of people who inject drugs and persons with substance use disorders (SUD). It also examines various monitoring strategies that can be used during HCV treatment and follow-up for hard-to-reach populations.
Myth-Busting HCV Treatment: Interdisciplinary HCV Screening, Treatment and Follow-up (New England AETC, December 2021) – This part of the “Myth-Busting HCV Treatment” series focuses on the role of an interdisciplinary team in completing the essential components of HCV treatment assessment, service delivery for marginalized populations, and outreach to individuals experiencing SUD.
Myth-Busting HCV Treatment: Integrated Models of HCV Care Delivery (New England AETC, November 2021) – This part of the “Myth-Busting HCV Treatment” series describes the process of care and patient outcomes in a practice serving young injection drug users with integrated HCV treatment services and opioid use disorder services.
ConnQuER HepC?App: Educational and Care Companion App (New England AETC, October 2021) – This educational tool “is useful for patients, case managers, and community health workers. It is designed to inform about the clinical condition of hepatitis C and foster more efficient conversations between patients and healthcare providers.” It is part of the ConnQuer HepC project aimed at curing HCV among people of color with HIV.